|
Mutation Information
|
Mutation Site
|
G1862T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Combined Mutation
|
bcp.G1764A+bcp.A1762T+prec.G1862T |
|
Nucleotide_Mutation
|
V17F |
|
Genotype/Subtype
|
A |
|
Viral Reference
|
AF160501;
X75663;
X75657;
X72702;
X01587;
D00331;
X70185 |
|
Country
|
India |
Literature Information
|
PubMed PMID
|
16789012
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2006 |
|
Journal
|
Journal of medical virology |
|
Title
|
Basal core promoter, precore region mutations of HBV and their association with e antigen, genotype, and severity of liver disease in patients with chronic hepatitis B in India. |
|
Author
|
Chauhan R,Kazim SN,Bhattacharjee J,Sakhuja P,Sarin SK |
|
Evidence
|
The Pc G1896A mutation was more common in HBeAg-negative (33% vs. 2%, P < 0.01) patients and was genotype D specific. The Pc G1862T mutation was detected more often in HBeAg-positive than HBeAg-negative (37% vs. 11%, P < 0.01) patients and was genotype A specific (P < 0.01).
|
|
|
HBV Mutation Detail Information