|
Mutation Information
|
Mutation Site
|
G1764A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Viral Reference
|
LC500247.1;
LC365290.1 |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
33947693
|
|
Clinical information
|
Yes
|
|
Disease
|
Liver cirrhosis;
Hepatocellular carcinoma
|
|
Published Year
|
2021 |
|
Journal
|
Clinical cancer research : an official journal of the American Association for Cancer Research |
|
Title
|
The Landscape of Cell-Free HBV Integrations and Mutations in Cirrhosis and Hepatocellular Carcinoma Patients. |
|
Author
|
Zheng B,Liu XL,Fan R,Bai J,Wen H,Du LT,Jiang GQ,Wang CY,Fan XT,Ye YN,Qian YS,Wang YC,Liu GJ,Deng GH,Shen F,Hu HP,Wang H,Zhang QZ,Ru LL,Zhang J,Gao YH,Xia J,Yan HD,Liang MF,Yu YL,Sun FM,Gao YJ,Sun J,Zhong CX,Wang Y,Kong F,Chen JM,Zheng D,Yang Y,Wang CX,Wu L,Hou JL,Liu JF,Wang HY,Chen L |
|
Evidence
|
In HBV, genotype C of HCC, the mutation rate of A1762T and G1764A was 75.9% and 82.1%, respectively, whereas in HBV genotype B of HCC, the mutation rate of nt1762 and nt1764 was 35% and 31.6%, respectively.
|
|
|
HBV Mutation Detail Information