|
Mutation Information
|
Mutation Site
|
G1764A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Combined Mutation
|
bcp.G1764A+bcp.A1762T |
|
Genotype/Subtype
|
F |
|
Country
|
Alaskan |
Literature Information
|
PubMed PMID
|
29893492
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2019 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
An Association Between Core Mutations in Hepatitis B Virus Genotype F1b and Hepatocellular Carcinoma in Alaskan Native People. |
|
Author
|
Hayashi S,Khan A,Simons BC,Homan C,Matsui T,Ogawa K,Kawashima K,Murakami S,Takahashi S,Isogawa M,Ikeo K,Mizokami M,McMahon BJ,Tanaka Y |
|
Evidence
|
In the HCC patients, T1938C and A2051C mutations in the core region had accumulated significantly with A1762T/G1764A mutations in the basal core promoter (BCP) region and G1896A mutation in the precore (PC) region.
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HBV Mutation Detail Information