HBV Mutation Detail Information

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Mutation Information
Mutation Site G1764A
Mutation Type Nucleotide level
Gene/Protein/Region Type BCP
Combined Mutation bcp.G1764A+bcp.A1762T
Genotype/Subtype E
Country Sudan
Literature Information
PubMed PMID 25449246
Disease HBV-HIV coinfection
Published Year 2014
Journal International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Title Genotyping and virological characteristics of hepatitis B virus in HIV-infected individuals in Sudan.
Author Yousif M,Mudawi H,Hussein W,Mukhtar M,Nemeri O,Glebe D,Kramvis A
Evidence Of the six isolates from HBeAg-positive sera, two had mutations at the BCP: SDH052 (HBsAg-positive, genotype D) had A1762G, and SDH084 (HBsAg-positive, genotype E) had A1762T/G1764A. The remaining four isolates, from HBeAg-positive patients, had wild-type BCP/PC. Thirty of the 44 isolates from HBeAg-negative individuals (17 HBsAg-positive and 13 HBsAg-negative) were successfully amplified and sequenced in the BCP/PC region.

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Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation