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Mutation Information
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Mutation Site
|
G1764A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Genotype/Subtype
|
C |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
22523569
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2012 |
|
Journal
|
PloS one |
|
Title
|
Dynamics of hepatitis B virus quasispecies in association with nucleos(t)ide analogue treatment determined by ultra-deep sequencing. |
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Author
|
Nishijima N,Marusawa H,Ueda Y,Takahashi K,Nasu A,Osaki Y,Kou T,Yazumi S,Fujiwara T,Tsuchiya S,Shimizu K,Uemoto S,Chiba T |
|
Evidence
|
For example, in chronic infection, G to A point mutation at nucleotide (nt) 1896 in the pre-core (pre-C) region as well as A1762T and G1764A mutations in the core-promoter region are highly associated with HBeAg seroconversion that in general results in the low levels of viremia and consequent clinical cure.
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HBV Mutation Detail Information