Mutation Information
Mutation Site
|
G1764A |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
BCP |
Combined Mutation
|
bcp.G1764A+bcp.A1762T |
Literature Information
PubMed PMID
|
18410611
|
Disease
|
Acute exacerbation of chronic hepatitis B
|
Published Year
|
2008 |
Journal
|
Journal of gastroenterology and hepatology |
Title
|
Detection of HBV core promoter and precore mutations helps distinguish flares of chronic hepatitis from acute hepatitis B. |
Author
|
Kusumoto K,Yatsuhashi H,Nakao R,Hamada R,Fukuda M,Tamada Y,Taura N,Komori A,Daikoku M,Hamasaki K,Nakao K,Ishibashi H,Miyakawa Y,Eguchi K |
Evidence
|
RESULTS: Mutations in the core promoter (A1762T/G1764A) and precore region (G1896A) were more frequent in patients with acute exacerbation of chronic hepatitis than Acute hepatitis B (81% vs 19%; P < 0.
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