|
Mutation Information
|
Mutation Site
|
G1764A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
C Promoter |
Literature Information
|
PubMed PMID
|
15968338
|
|
Published Year
|
2005 |
|
Journal
|
International journal of medical sciences |
|
Title
|
Natural History and Clinical Consequences of Hepatitis B Virus Infection. |
|
Author
|
Pan CQ,Zhang JX |
|
Evidence
|
Most frequent precore mutation is a G-A change at nucleotide 1896 (G1896A) which creates a stop codon and results in loss of HBeAg synthesis; the most common core promoter mutation involves a 2 nucleotide substitution at nucleotide 1762 and 1764.
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HBV Mutation Detail Information