HBV Mutation Detail Information

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Mutation Information
Mutation Site G1764A
Mutation Type Nucleotide level
Gene/Protein/Region Type C Promoter
Genotype/Subtype A;D;F
Relevant Drug lamivudine (LAM)
Country Korea
Literature Information
PubMed PMID 15932365
Disease Chronic hepatitis B
Published Year 2005
Journal Alimentary pharmacology & therapeutics
Title Changes in different regions of hepatitis B virus gene in hepatitis B 'e' antigen-negative patients with chronic hepatitis B: the effect of long-term lamivudine therapy.
Author Buti M,Jardi R,Rodriguez-Frias F,Valdes A,Schaper M,Esteban R,Guardia J
Evidence DNA sequence analysis of the core promoter region (nucleotides 1762 and 1764) showed that six patients had core promoter changes in the serum samples collected at baseline, both at nucleotide 1762 (A1762T) and at nucleotide 1764 (G1764A; Table 3).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation