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Mutation Information
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Mutation Site
|
G1757A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Genotype/Subtype
|
D |
|
Viral Reference
|
X02763
|
|
Country
|
Iran |
Literature Information
|
PubMed PMID
|
16099903
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2005 |
|
Journal
|
The Journal of general virology |
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Title
|
T1764G1766 core promoter double mutants are restricted to Hepatitis B virus strains with an A1757 and are common in genotype D. |
|
Author
|
Sendi H,Mehrab-Mohseni M,Zali MR,Norder H,Magnius LO |
|
Evidence
|
When this double mutation was associated with G1757, it was linked to a higher virus load in patients than when it was associated with A1757 (10(5.2+/-1.8) vs 10(3.2+/-0.8) copies ml(-1); P=0.004).
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HBV Mutation Detail Information