Mutation Information
Mutation Site
|
G1742A |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
BCP |
Genotype/Subtype
|
A |
Literature Information
PubMed PMID
|
27473751
|
Published Year
|
2016 |
Journal
|
The Journal of general virology |
Title
|
Enhanced pregenomic RNA levels and lowered precore mRNA transcription efficiency in a genotype A hepatitis B virus genome with C1766T and T1768A mutations obtained from a fulminant hepatitis patient. |
Author
|
Nishizawa T,Hoshino T,Naganuma A,Kobayashi T,Nagashima S,Takahashi M,Takagi H,Okamoto H |
Evidence
|
We recently found four unique mutations [G to A at nucleotide 1742 (G1742A), C1766T, T1768A and T1809C] in the basal core promoter (BCP) region of a genotype A hepatitis B virus (HBV) strain (FH) obtained from a 53-year-old man with fatal fulminant hepatitis.
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