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Mutation Information
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Mutation Site
|
G1728A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Genotype/Subtype
|
E |
|
Relevant Drug
|
zidovudine (AZT);lamivudine (LAM);nevirapine (NPV) |
|
Country
|
Namibia |
Literature Information
|
PubMed PMID
|
32915862
|
|
Disease
|
HBV-HIV coinfection
|
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Published Year
|
2020 |
|
Journal
|
PloS one |
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Title
|
Hepatitis B virus drug resistance mutations in HIV/HBV co-infected children in Windhoek, Namibia. |
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Author
|
Tamandjou Tchuem CR,Brandt L,Nel ER,Cotton MF,Matthews P,Kaindjee-Tjituka F,Preiser W,Andersson MI |
|
Evidence
|
Additional substitutions were observed in the upper regulatory region (URR) and BCP regions: patient 2C carried the HBV URR mutant G1728A and BCP mutant G1764T/C1766G, and HBV from patients 6C and 7C carried BCP T1768A and URR C1678T mutants, respectively.
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HBV Mutation Detail Information