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Mutation Information
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Mutation Site
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G1719T |
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Mutation Type
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Nucleotide level |
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Gene/Protein/Region Type
|
EnhII |
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Country
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China |
Literature Information
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PubMed PMID
|
20959817
|
|
Disease
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Chronic hepatitis B;
Liver cirrhosis;
Hepatocellular carcinoma
|
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Published Year
|
2011 |
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Journal
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The American journal of gastroenterology |
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Title
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Association between the various mutations in viral core promoter region to different stages of hepatitis B, ranging of asymptomatic carrier state to hepatocellular carcinoma. |
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Author
|
Yin J,Xie J,Liu S,Zhang H,Han L,Lu W,Shen Q,Xu G,Dong H,Shen J,Zhang J,Han J,Wang L,Liu Y,Wang F,Zhao J,Zhang Q,Ni W,Wang H,Cao G |
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Evidence
|
C1653T, T1674C, G1719T, A1762T, and A1846T were significantly associated with HCC, whereas A1652G, C1673T, A1726C,A1727T, C1730G, T1768A, C1773T, and C1799G were inverselyassociated with HCC, as compared with the patients with LC in the genotype C HBV-infected patients seronegative for HBeAg.
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HBV Mutation Detail Information