HBV Mutation Detail Information

> G167T Search Result


Mutation Information
Mutation Site G167T
Mutation Type Nucleotide level
Gene/Protein/Region Type S
Viral Reference LC500247.1
Country China
Literature Information
PubMed PMID 33947693
Clinical information Yes
Disease Liver cirrhosis; Hepatocellular carcinoma
Published Year 2021
Journal Clinical cancer research : an official journal of the American Association for Cancer Research
Title The Landscape of Cell-Free HBV Integrations and Mutations in Cirrhosis and Hepatocellular Carcinoma Patients.
Author Zheng B,Liu XL,Fan R,Bai J,Wen H,Du LT,Jiang GQ,Wang CY,Fan XT,Ye YN,Qian YS,Wang YC,Liu GJ,Deng GH,Shen F,Hu HP,Wang H,Zhang QZ,Ru LL,Zhang J,Gao YH,Xia J,Yan HD,Liang MF,Yu YL,Sun FM,Gao YJ,Sun J,Zhong CX,Wang Y,Kong F,Chen JM,Zheng D,Yang Y,Wang CX,Wu L,Hou JL,Liu JF,Wang HY,Chen L
Evidence As to genotype B, five HBV mutation hotspots were found significantly associated with HCC, among which A2721G, T2666C, A636T, and G167T (OR > 3) were identified as high-risk factors, whereas six mutation hotspots were inversely associated with HCC, as compared with patients with LC.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation