Mutation Information
Mutation Site
|
G1613A |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
C Promoter |
Country
|
Korea |
Literature Information
PubMed PMID
|
24344773
|
Disease
|
Hepatocellular carcinoma
|
Published Year
|
2014 |
Journal
|
Journal of viral hepatitis |
Title
|
Combinations of eight key mutations in the X/preC region and genomic activity of hepatitis B virus are associated with hepatocellular carcinoma. |
Author
|
Park YM,Jang JW,Yoo SH,Kim SH,Oh IM,Park SJ,Jang YS,Lee SJ |
Evidence
|
Accumulation of eight key mutations located in the X/preC regions of the hepatitis B virus (HBV) genome (G1613A, C1653T, T1753V, A1762T, G1764A, A1846T, G1896A and G1899A) is a risk marker for the development of hepatocellular carcinoma (HCC).
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