|
Mutation Information
|
Mutation Site
|
G159* |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Viral Reference
|
X85254.1;
M32138.1;
FJ904433.1;
AF121240.1;
X65259.1 |
|
Immune Escape
|
Y |
|
Country
|
Iran |
Literature Information
|
PubMed PMID
|
31105017
|
|
Disease
|
Hepatocellular carcinoma;
Liver cirrhosis
|
|
Published Year
|
2019 |
|
Journal
|
Annals of hepatology |
|
Title
|
Association of HBsAg mutation patterns with hepatitis B infection outcome: Asymptomatic carriers versus HCC/cirrhotic patients. |
|
Author
|
Hosseini SY,Sanaei N,Fattahi MR,Malek-Hosseini SA,Sarvari J |
|
Evidence
|
Stop codon mutations which cause a truncated form to HBsAg including C69*(N = 6), W182*(N = 2), L94*, L95*, C107* and G159* were observed in 47.4% of individuals in the HCC/cirrhotic group, but only one (L216*) was detected among the asymptomatic cases (P > 0.001).
|
|
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HBV Mutation Detail Information