HTLV1 Mutation Detail Information

> G148V Search Result

Mutation Information

Mutation Site	G148V
Mutation Type	Amino acid level
Gene/Protein/Region Type	Tax

Literature Information

PubMed PMID	31299491
Published Year	2019
Journal	Virology
Title	The human T-cell leukemia virus type-1 tax oncoprotein dissociates NF-κB p65RelA-Stathmin complexes and causes catastrophic mitotic spindle damage and genomic instability.
Author	Malu A,Hutchison T,Yapindi L,Smith K,Nelson K,Bergeson R,Pope J,Romeo M,Harrod C,Ratner L,Van Lint C,Harrod R
Evidence	The Tax-G148V mutant, defective for NF-kappaB activation, exhibited reduced p65RelA-Stathmin binding and diminished genomic instability and cytotoxicity.

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation