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Mutation Information
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Mutation Site
|
G145T |
|
Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
E6 |
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Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
AF125673.1
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Literature Information
|
PubMed PMID
|
27806689
|
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Published Year
|
2016 |
|
Journal
|
BMC genomics |
|
Title
|
Functional variants of human papillomavirus type 16 demonstrate host genome integration and transcriptional alterations corresponding to their unique cancer epidemiology. |
|
Author
|
Jackson R,Rosa BA,Lameiras S,Cuninghame S,Bernard J,Floriano WB,Lambert PF,Nicolas A,Zehbe I |
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Evidence
|
The variant-specific non-synonymous SNPs (relative to the reference HPV16 W12E genome) present in EPE6 (G350T) and AAE6 (G145T+C335T) were confirmed with depth of reads of 6x for EPE6 and with 14x to ~300x depth of reads for AAE6.
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HPV Mutation Detail Information