Mutation Information
Mutation Site
|
G145T |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
E6 |
Nucleotide_Mutation
|
Q14H |
Genotype/Subtype
|
HPV16 |
Viral Reference
|
K02718.1
|
Literature Information
PubMed PMID
|
22524831
|
Disease
|
Cervical carcinoma
|
Published Year
|
2012 |
Journal
|
Asian Pacific journal of cancer prevention : APJCP |
Title
|
Whole genome analysis of human papillomavirus type 16 multiple infection in cervical cancer patients. |
Author
|
Chansaenroj J,Theamboonlers A,Junyangdikul P,Swangvaree S,Karalak A,Poovorawan Y |
Evidence
|
The E6 gene of the 8 whole genome sequences showed 7 mutation points; 3 (42.9%) were synonymous mutations while 4 (57.1%) were non synonymous mutations with amino acid substitutions at Q14H (nt G145T), D25E (nt T178G), H78Y (nt C335T), L83V (nt T350G) (Table 2).
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