|
Mutation Information
|
Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Immune Escape
|
Y |
Literature Information
|
PubMed PMID
|
32824318
|
|
Published Year
|
2020 |
|
Journal
|
Vaccines |
|
Title
|
Cross-Protection of Hepatitis B Vaccination among Different Genotypes. |
|
Author
|
Inoue T,Tanaka Y |
|
Evidence
|
This virus has a G587A mutation, resulting in a G145R substitution of the “a” determinant of the surface antigen. Because the G145R substitution changes the projecting second loop of the “a” determinant, neutralizing antibodies induced by vaccination no longer recognize the mutated epitope
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HBV Mutation Detail Information