HBV Mutation Detail Information

> G145R Search Result


Mutation Information
Mutation Site G145R
Mutation Type Amino acid level
Gene/Protein/Region Type S
Viral Reference AB697502; AB246345; JQ801515; AB246346; JQ801516; AB246339; AB900105; AB246342
Country Japan
Literature Information
PubMed PMID 30584239
Disease HBV infection
Published Year 2018
Journal Scientific reports
Title Expansion of viral variants associated with immune escape and impaired virion secretion in patients with HBV reactivation after resolved infection.
Author Inuzuka T,Ueda Y,Arasawa S,Takeda H,Matsumoto T,Osaki Y,Uemoto S,Seno H,Marusawa H
Evidence In addition, several variants in the immunodominant loop of surface protein, including sT118K, sQ129H, and sG145R substitutions in the small S protein are reported to induce impaired virion secretion from infected liver cells

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation