HBV Mutation Detail Information

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Mutation Information
Mutation Site G145R
Mutation Type Amino acid level
Gene/Protein/Region Type S
Genotype/Subtype F
Relevant Drug entecavir (ETV)
Country Germany
Literature Information
PubMed PMID 30079137
Disease Acute hepatitis B
Published Year 2018
Journal World journal of hepatology
Title Hepatitis B virus subgenotype F3 reactivation with vaccine escape mutations: A case report and review of the literature.
Author Schlabe S,van Bremen K,Aldabbagh S,Glebe D,Bremer CM,Marsen T,Mellin W,Cristanziano VD,Eis-Hübinger AM,Spengler U
Evidence We examined the effects of two closely related CpAMs, HAP12 and HAP13, which differ by a single atom but have drastically different antiviral activities, on the assembly of wild-type Cp and three T109 mutants (T109M, T109I, and T109S) that display a range of resistances.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation