|
Mutation Information
|
Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
C |
|
Immune Escape
|
Y |
|
Country
|
Vietnam |
Literature Information
|
PubMed PMID
|
28859616
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2017 |
|
Journal
|
BMC infectious diseases |
|
Title
|
Molecular characterization of hepatitis B virus in Vietnam. |
|
Author
|
Bui TTT,Tran TT,Nghiem MN,Rahman P,Tran TTT,Dinh MNH,Le MH,Nguyen VVC,Thwaites G,Rahman M |
|
Evidence
|
Among the isolates, 8.1% (11/135) had a mutation in the “a” determinant region including 2.2% (3/135) P120S/T, 2.2% (3/135) I/T126S/A, 3% (4/135) M133 L/T and 0.7% (1/135) G145R. There were no significant differences in the mutations between genotype B and C isolates (Table (Table22).
|
|
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HBV Mutation Detail Information