|
Mutation Information
|
Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Immune Escape
|
Y |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
28198078
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2017 |
|
Journal
|
Journal of medical virology |
|
Title
|
Mutation in the S gene of hepatitis B virus and anti-HBs subtype-nonspecificity contributed to the co-existence of HBsAg and anti-HBs in patients with chronic hepatitis B virus infection. |
|
Author
|
Fu X,Chen J,Chen H,Lin J,Xun Z,Li S,Liu C,Zeng Y,Chen T,Yang B,Ou Q |
|
Evidence
|
Besides, some HBsAg variations in group I patients, sG145R mutation, inserted mutations, and continuous aa mutations within the major hydrophilic region (MHR), decreased the neutralized capacity of anti-HBs from HBV vaccinated persons.
|
|
|
HBV Mutation Detail Information