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Mutation Information
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Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
Literature Information
|
PubMed PMID
|
25483515
|
|
Published Year
|
2015 |
|
Journal
|
Human vaccines & immunotherapeutics |
|
Title
|
Hepatitis B vaccination. |
|
Author
|
Romanò L,Paladini S,Galli C,Raimondo G,Pollicino T,Zanetti AR |
|
Evidence
|
Since the G145R substitution alters the projecting loop (aa 139-147) of the a determinant, the neutralizing antibodies induced by vaccination are no longer able to recognize the mutated epitope.
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HBV Mutation Detail Information