|
Mutation Information
|
Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
C |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Australia |
Literature Information
|
PubMed PMID
|
24329944
|
|
Disease
|
HBV infection
|
|
Published Year
|
2014 |
|
Journal
|
Journal of viral hepatitis |
|
Title
|
Short duration of lamivudine for the prevention of hepatitis B virus transmission in pregnancy: lack of potency and selection of resistance mutations. |
|
Author
|
Ayres A,Yuen L,Jackson KM,Manoharan S,Glass A,Maley M,Yoo W,Hong SP,Kim SO,Luciani F,Bowden DS,Bayliss J,Levy MT,Locarnini SA |
|
Evidence
|
This mother was also infected with the vaccine escape variant (sG145R), which was inhibited by LMV treatment.
|
|
|
HBV Mutation Detail Information