|
Mutation Information
|
Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
C |
|
Viral Reference
|
X04615
|
|
Relevant Drug
|
lamivudine (LAM);entecavir (ETV) |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
24157033
|
|
Disease
|
HBV infection
|
|
Published Year
|
2013 |
|
Journal
|
Transplantation proceedings |
|
Title
|
Analysis of S gene mutation of the hepatitis B virus in adult liver transplant recipients showing resistance to hepatitis B immunoglobulin therapy. |
|
Author
|
Park GC,Hwang S,Ahn CS,Kim KH,Moon DB,Ha TY,Song GW,Jung DH,Shin YW,Kim SH,Chang KH,Namgoong JM,Park CS,Park HW,Park YH,Kang SH,Jung BH,Lee SG |
|
Evidence
|
RESULTS: Various mutations in the MHR were observed in 14/15 samples: Gly145Arg mutation in 8/13 Adr subtype and 1/2 Ayw subtype samples (60%).
|
|
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HBV Mutation Detail Information