HBV Mutation Detail Information

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Mutation Information

Mutation Site	G145R
Mutation Type	Amino acid level
Gene/Protein/Region Type	S

Literature Information

PubMed PMID	24076590
Published Year	2013
Journal	Iranian journal of immunology : IJI
Title	Construction and expression of hepatitis B surface antigen escape variants within the "a" determinant by site directed mutagenesis.
Author	Golsaz Shirazi F,Amiri MM,Mohammadi H,Bayat AA,Roohi A,Khoshnoodi J,Zarnani AH,Jeddi-Tehrani M,Kardar GA,Shokri F
Evidence	RESULTS: Ten HBsAg mutants having single mutation within the "a" determinant including P120E, T123N, Q129H, M133L, K141E, P142S, D144A, G145R, N146S and C147S together with a wt form were successfully constructed and expressed in CHO cells.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation