Mutation Information
Mutation Site
|
G145R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Genotype/Subtype
|
D |
Viral Reference
|
X02496
|
Immune Escape
|
Y |
Country
|
Greece |
Literature Information
PubMed PMID
|
23773581
|
Disease
|
Fulminant hepatitis B
|
Published Year
|
2013 |
Journal
|
Transplant infectious disease : an official journal of the Transplantation Society |
Title
|
Renal transplantation from hepatitis B surface antigen (HBsAg)-positive donors to HBsAg-negative recipients: a case of post-transplant fulminant hepatitis associated with an extensively mutated hepatitis B virus strain and review of the current literature. |
Author
|
Magiorkinis E,Paraskevis D,Pavlopoulou ID,Kantzanou M,Haida C,Hatzakis A,Boletis IN |
Evidence
|
RESULTS: Molecular analysis revealed multiple mutations in various open reading frames of HBV, the most important being the G145R escape mutation and a frameshift mutation-insertion (1838insA) within the pre-C/C reading frame.
|
|
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