HBV Mutation Detail Information

> G145R Search Result


Mutation Information
Mutation Site G145R
Mutation Type Amino acid level
Gene/Protein/Region Type S
Genotype/Subtype D
Viral Reference X02496
Immune Escape Y
Country Greece
Literature Information
PubMed PMID 23773581
Disease Fulminant hepatitis B
Published Year 2013
Journal Transplant infectious disease : an official journal of the Transplantation Society
Title Renal transplantation from hepatitis B surface antigen (HBsAg)-positive donors to HBsAg-negative recipients: a case of post-transplant fulminant hepatitis associated with an extensively mutated hepatitis B virus strain and review of the current literature.
Author Magiorkinis E,Paraskevis D,Pavlopoulou ID,Kantzanou M,Haida C,Hatzakis A,Boletis IN
Evidence RESULTS: Molecular analysis revealed multiple mutations in various open reading frames of HBV, the most important being the G145R escape mutation and a frameshift mutation-insertion (1838insA) within the pre-C/C reading frame.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation