|
Mutation Information
|
Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
C |
|
Viral Reference
|
AF286594
|
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
23710315
|
|
Clinical information
|
Yes
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2013 |
|
Journal
|
Gut and liver |
|
Title
|
Quasispecies and pre-existing drug-resistant mutations of hepatitis B virus in patients with chronic hepatitis B. |
|
Author
|
Kim DY,Chang HY,Lim SM,Kim SU,Park JY,Kim JK,Lee KS,Han KH,Chon CY,Ahn SH |
|
Evidence
|
All patients showed at least one kind of concomitant envelope gene change, which overlaps the polymerase gene. In patient 1, changes of the P gene, rtW153Q, rtI169L, rtV173L, rtA181V, and rtM204V, corresponded to change of the S gene, sG145R, sF161H, sE164D, and s195M, respectively (Table 4).
|
|
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HBV Mutation Detail Information