HBV Mutation Detail Information

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Mutation Information

Mutation Site	G145R
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Country	Russia

Literature Information

PubMed PMID	23265059
Disease	Chronic hepatitis B
Published Year	2012
Journal	Klinicheskaia laboratornaia diagnostika
Title	[The panels of serums, containing various subtypes and mutant forms of HBsAg, to evaluate the diagnostics sensitivity of kits oa reagents detecting HBsAg].
Author	Kozhanova TV,Klushkina VV,Isaeva OV,Popova OE,Netesova IG,Kiuregian KK,Mikhaĭlov MI
Evidence	The testing of reagents kits to detect HBsAg using twi panels containing recombinant and native variants of HBsAg, demonstrated that these kits enable to detect various sero-vatriants of HBsAg (ayw2, adw2, ayw3varA, ayw3varB, adrq-) in concentration 0.1-0.01 IU/l and the so called elusive mutant forms of HBsAg of recombinant and native origin (G145R, Q129R, Q129H, Q129L, T143K, T126N, T126S, D144A, M133L, K141E and P142S).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation