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Mutation Information
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Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
B |
|
Viral Reference
|
Y18855;
X75656;
GQ377635;
DQ315780;
DQ315779;
AY902776;
AY293309;
AY161157;
AY090458;
AY090457;
AJ132335;
AJ012207;
AF536524;
AF241410;
AF223961;
AF151735;
AF121245;
AB241110;
AB241109;
AB219427;
AB219426;
AB205119;
AB194951;
AB194948;
AB106885;
AB105172;
AB091255;
AB090269;
AB078033;
AB076678;
AB074047;
AB073851;
AB073834;
AB064313;
AB064311;
AB048701;
AB036909;
AB033559;
AB033554;
AB031267;
AB031262;
AB026814;
AB014374;
AB014360;
AB010290 |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
22669316
|
|
Disease
|
HBV infection
|
|
Published Year
|
2012 |
|
Journal
|
Archives of virology |
|
Title
|
Molecular epidemiological study of hepatitis B virus in blood donors from five Chinese blood centers. |
|
Author
|
Liu Y,Wang J,Huang Y,Yang T,Guo X,Li J,Wen G,Yun Z,Zeng P,He M,Xu M,Liu G,Ke L,Wright D,Liu J,Nelson K,Shan H |
|
Evidence
|
The proportion of MHR mutations varied by subtype (Table 3, p = 0.001), where only 2 of 53 (3.8 %) subjects with MHR mutations belonged to subtype adrq+, and the proportion of MHR mutations was higher among subtype adw (19.4 %) and higher again among subtype ayw (35.0 %). One isolate was found with the G145R mutation, which is one of the most important mutations in the HBV S region.
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HBV Mutation Detail Information