|
Mutation Information
|
Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Country
|
Turkey |
Literature Information
|
PubMed PMID
|
22224083
|
|
Disease
|
HBV infection
|
|
Published Year
|
2011 |
|
Journal
|
Hepatitis monthly |
|
Title
|
Frequency and mutation patterns of resistance in patients with chronic hepatitis B infection treated with nucleos(t)ide analogs in add-on and switch strategies. |
|
Author
|
Sayan M,Akhan SC,Senturk O |
|
Evidence
|
Two patients in the add-on therapy group had sC137G amino acid substitutions (with rtL80M + rtM204I mutations), 2 patients in the switch therapy group had sG145R mutations (with rtN236T mutations), and 4 patients in the switch therapy group had sD144E mutations (1 patient with rtL80M + rtM204V mutations and 3 patients with rtQ215S mutations).
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HBV Mutation Detail Information