|
Mutation Information
|
Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Viral Reference
|
AY090460;
AF160501;
X75658;
X75657;
V01460;
X01587;
D00329;
X02763 |
|
Immune Escape
|
Y |
|
Country
|
America |
Literature Information
|
PubMed PMID
|
21723325
|
|
Disease
|
HBV infection
|
|
Published Year
|
2011 |
|
Journal
|
Journal of virological methods |
|
Title
|
Development and validation of a hepatitis B virus DNA sequencing assay for assessment of antiviral resistance, viral genotype and surface antigen mutation status. |
|
Author
|
Mallory MA,Page SR,Hillyard DR |
|
Evidence
|
The escape mutation sG145R in the surface antigen was identified in 0.8% of patient samples. Infections with genotypes A, B, C, D, E, F, G and H were observed in 36.6%, 19.6%, 21.7%, 13.5%, 3.6%, 0.7%, 2.2%, and 0.5% of patient samples respectively.
|
|
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HBV Mutation Detail Information