HBV Mutation Detail Information

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Mutation Information
Mutation Site G145R
Mutation Type Amino acid level
Gene/Protein/Region Type S
Genotype/Subtype D
Immune Escape Y
Country Italy
Literature Information
PubMed PMID 17134939
Disease Occult HBV infection
Published Year 2007
Journal Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Title Reactivation of an occult hepatitis B virus escape mutant in an anti-HBs positive, anti-HBc negative lymphoma patient.
Author Awerkiew S,Däumer M,Reiser M,Wend UC,Pfister H,Kaiser R,Willems WR,Gerlich WH
Evidence The virus exhibited three S gene mutations (L109R, C137W, G145R) which led to false negative HBsAg results and diminished binding of vaccine-induced anti-HBs.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation