|
Mutation Information
|
Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Combined Mutation
|
rt.S223A+s.G145R |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
16830379
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2006 |
|
Journal
|
World journal of gastroenterology |
|
Title
|
Mutations in surface and polymerase gene of chronic hepatitis B patients with coexisting HBsAg and anti-HBs. |
|
Author
|
Lu HY,Zeng Z,Xu XY,Zhang NL,Yu M,Gong WB |
|
Evidence
|
Six (14.6%) out of 41 mutations were located at the “α” determinant region, and 4 mutations were presented in the first loop (positions 124-137), the others were in the second loop (positions 139-147, S143T, G145R).
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HBV Mutation Detail Information