|
Mutation Information
|
Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Amino acid_Mutation
|
G587A |
|
Relevant Drug
|
hepatitis B immunoglobulin (HBIG) |
Literature Information
|
PubMed PMID
|
16622882
|
|
Published Year
|
2006 |
|
Journal
|
Journal of medical virology |
|
Title
|
Infections by hepatitis B surface antigen gene mutants in Europe and North America. |
|
Author
|
Tabor E |
|
Evidence
|
In some cases, these mutations have included a glycine to arginine substitution at position 145 (G145R), which results in a conformational change and different reactivity to monoclonal antibody reagents than that of the wild-type virus.
|
|
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HBV Mutation Detail Information