Mutation Information
Mutation Site
|
G145R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Combined Mutation
|
s.G145R+s.T126S;s.G145R+s.D144A |
Country
|
Thailand |
Literature Information
PubMed PMID
|
16553556
|
Published Year
|
2006 |
Journal
|
Viral immunology |
Title
|
HBsAg diagnostic kits in the detection of hepatitis B virus mutation within "a" determinant. |
Author
|
Louisirirotchanakul S,Kanoksinsombat C,O'Charoen R,Fongsatikul L,Puapairoj C,Lulitanond V,Appassakij H,Promwong C,Wasi C |
Evidence
|
Interestingly, any commercial kits with monoclonal antibody capture and polyclonal antibody detection (mono/poly), but not mono/mono Ab capture and detection, could pick up the common HBsAg Gly145Arg mutant either solely or in combination with other mutations within the "a" determinant.
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