|
Mutation Information
|
Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
B |
|
Immune Escape
|
Y |
|
Country
|
Taiwan;China |
Literature Information
|
PubMed PMID
|
15361503
|
|
Disease
|
HBV infection
|
|
Published Year
|
2004 |
|
Journal
|
Gut |
|
Title
|
Survey of hepatitis B surface variant infection in children 15 years after a nationwide vaccination programme in Taiwan. |
|
Author
|
Hsu HY,Chang MH,Ni YH,Chen HL |
|
Evidence
|
The prevalence of a determinant mutants in HBV-DNA positive children was 7.8% (8/103) in 1984, which significantly increased to 19.6% (10/51) in 1989, peaked at 28.1% (9/32) in 1994, and remained at 23.1% ((3/13) (T131I, G145R, G145R)) in 1999
|
|
|
HBV Mutation Detail Information