Mutation Information
Mutation Site
|
G145R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Genotype/Subtype
|
D |
Literature Information
PubMed PMID
|
11481624
|
Disease
|
Fulminant hepatitis B
|
Published Year
|
2001 |
Journal
|
Hepatology (Baltimore, Md.) |
Title
|
A dominant hepatitis B virus population defective in virus secretion because of several S-gene mutations from a patient with fulminant hepatitis. |
Author
|
Kalinina T,Riu A,Fischer L,Will H,Sterneck M |
Evidence
|
This was caused by a combination of amino acid changes in the S-protein including the mutation G145R frequently emerging after hyperimmunoglobulin treatment.
|
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