|
Mutation Information
|
Mutation Site
|
G145A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Immune Escape
|
Y |
|
Country
|
Vietnam |
Literature Information
|
PubMed PMID
|
22720022
|
|
Disease
|
HBV-HCV-HIV coinfection
|
|
Published Year
|
2012 |
|
Journal
|
PloS one |
|
Title
|
A multicentre molecular analysis of hepatitis B and blood-borne virus coinfections in Viet Nam. |
|
Author
|
Dunford L,Carr MJ,Dean J,Nguyen LT,Ta Thi TH,Nguyen BT,Connell J,Coughlan S,Nguyen HT,Hall WW,Thi LA |
|
Evidence
|
In the immunodominant 'a' region of the surface gene, point mutations were identified in 31% (n = 58/187) of sequences, and 2.2% (n = 4/187) and 5.3% (n = 10/187) specimens contained the major vaccine escape mutations G145A/R and P120L/Q/S/T, respectively.
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|
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HBV Mutation Detail Information