Mutation Information
Mutation Site
|
G145A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Genotype/Subtype
|
D |
Country
|
Russia |
Literature Information
PubMed PMID
|
22442974
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2012 |
Journal
|
Zhurnal mikrobiologii, epidemiologii i immunobiologii |
Title
|
[Heterogeneity of hepatitis B virus and diagnostic potential of modern test systems for the detection of HBsAg]. |
Author
|
Kuzin SN,Zabotina EE,Zabelin NN,Kudriavtseva EN,Samokhvalov EI,Borisova OV,Manina TA,Lisitsina EV,Kuzina LE,Malyshev NA,Lavrov VF |
Evidence
|
Amino acid substitutions G145A, M133I, S132T localized in the main hydrophilic region and P217L, S207N, V184A localized in the C-end of the protein C that are connected with diagnostic and vaccine escape were identified in 5 isolates.
|
|
|