HBV Mutation Detail Information

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Mutation Information
Mutation Site G145A
Mutation Type Amino acid level
Gene/Protein/Region Type S
Genotype/Subtype A
Immune Escape Y
Country Irish
Literature Information
PubMed PMID 18649329
Disease Acute hepatitis B
Published Year 2008
Journal Journal of medical virology
Title Molecular characterization of hepatitis B virus (HBV) isolates, including identification of a novel recombinant, in patients with acute HBV infection attending an Irish hospital.
Author Laoi BN,Crowley B
Evidence Variations within the S gene were identified in 6 isolates, including Gly145Ala, associated with vaccine immune escape, Asp144Glu, Ser143Leu and Phe134Leu, each associated with failure to detect HBsAg.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation