|
Mutation Information
|
Mutation Site
|
G145A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
A |
|
Immune Escape
|
Y |
|
Country
|
Irish |
Literature Information
|
PubMed PMID
|
18649329
|
|
Disease
|
Acute hepatitis B
|
|
Published Year
|
2008 |
|
Journal
|
Journal of medical virology |
|
Title
|
Molecular characterization of hepatitis B virus (HBV) isolates, including identification of a novel recombinant, in patients with acute HBV infection attending an Irish hospital. |
|
Author
|
Laoi BN,Crowley B |
|
Evidence
|
Variations within the S gene were identified in 6 isolates, including Gly145Ala, associated with vaccine immune escape, Asp144Glu, Ser143Leu and Phe134Leu, each associated with failure to detect HBsAg.
|
|
|
HBV Mutation Detail Information