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Mutation Information
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Mutation Site
|
G140S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Country
|
Nicaragua;Israel;Switzerland;France;US;Japan;Ethiopia |
Literature Information
|
PubMed PMID
|
32102090
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
PloS one |
|
Title
|
Analysis of unusual and signature APOBEC-mutations in HIV-1 pol next-generation sequences. |
|
Author
|
Tzou PL,Kosakovsky Pond SL,Avila-Rios S,Holmes SP,Kantor R,Shafer RW |
|
Evidence
|
There are 17 DRMs that could be caused by APOBEC-mediated G-to-A hypermutation: D30N, M46I, G48S, and G73S in PR, D67N, E138K, M184I, G190ES, and M230I in RT, and G118R, E138K, G140S, G163KR, D232N, and R263K in IN.
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HIV Mutation Detail Information