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Mutation Information
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Mutation Site
|
G132C |
|
Mutation Type
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Nucleotide level |
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Gene/Protein/Region Type
|
E6 |
|
Nucleotide_Mutation
|
R10T |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718.1
|
|
Country
|
Gabon |
Literature Information
|
PubMed PMID
|
27610192
|
|
Disease
|
Low grade squamous intraepithelial lesion;
High grade squamous intraepithelial lesion;
Cervical carcinoma
|
|
Published Year
|
2016 |
|
Journal
|
Infectious agents and cancer |
|
Title
|
Molecular analysis of human Papillomavirus detected among women positive for cervical lesions by visual inspection with acetic acid/Lugol's iodine (VIA/VILI) in Libreville, Gabon. |
|
Author
|
Moussavou PB,Koumakpayi IH,Nkili-Meyong AA,Labouba I,Bisvigou U,Chansi JK,Engohan-Aloghe C,Dissanami F,Ambounda N,Delannoy-Vieillard AS,Diancourt L,Nkoghe D,Leroy EM,Belembaogo E,Berthet N |
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Evidence
|
Fourteen nucleotide variations were found in the E6 region: nine non-synonymous mutations (G132C (R10T), G132T (R10I), C143G (Q14D), G145T (C51F), G255T (D64E), C256T (H78Y), T295G (L83V), C335T (H78Y) and T350G (L83V)) and five synonymous (silent) mutations (T109C, G196A, T286A, A289G and A403G).
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HPV Mutation Detail Information