|
Mutation Information
|
Mutation Site
|
G1317A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
X Promoter |
|
Genotype/Subtype
|
C |
|
Viral Reference
|
M12906;
X01587 |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
17888035
|
|
Disease
|
Chronic hepatitis B;
Hepatocellular carcinoma
|
|
Published Year
|
2007 |
|
Journal
|
Cancer science |
|
Title
|
Analysis of the complete hepatitis B virus genome in patients with genotype C chronic hepatitis and hepatocellular carcinoma. |
|
Author
|
Zhang KY,Imazeki F,Fukai K,Arai M,Kanda T,Mikata R,Yokosuka O |
|
Evidence
|
Compared with the wild type X promoter, the mutant type X promoters, M1 (G1317A), M2 (T1341C), and M4 (T1341G) showed increases in activity of 2.3, 3.8, and 1.4 times, respectively, in HepG2 cells.
|
|
|
HBV Mutation Detail Information