Mutation Information
Mutation Site
|
G130R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Combined Mutation
|
s.G130R+s.C124N+s.N146S |
Viral Reference
|
D00630;
M54923;
HPBAYW |
Immune Escape
|
Y |
Relevant Drug
|
fludarabine |
Country
|
Greek |
Literature Information
PubMed PMID
|
16789016
|
Disease
|
HBV infection
|
Published Year
|
2006 |
Journal
|
Journal of medical virology |
Title
|
Detection of a hepatitis B surface antigen variant emerging in a patient with chronic lymphocytic leukaemia treated with fludarabine. |
Author
|
Alexopoulou A,Dourakis SP,Pandelidaki H,Archimandritis AJ,Karayiannis P |
Evidence
|
patients and only 1 (2%) e-antigen-positive patient
|
|
|