HBV Mutation Detail Information

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Mutation Information
Mutation Site G130N
Mutation Type Amino acid level
Gene/Protein/Region Type S
Genotype/Subtype C
Viral Reference X04615
Country China
Literature Information
PubMed PMID 26613893
Disease Chronic hepatitis B
Published Year 2016
Journal The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
Title Mutations in the S gene and in the overlapping reverse transcriptase region in chronic hepatitis B Chinese patients with coexistence of HBsAg and anti-HBs.
Author Ding F,Miao XL,Li YX,Dai JF,Yu HG
Evidence Mutation sI126S/T within the "a" determinant was the most frequent change, and only patients from group I had the sQ129R, sG130N, sF134I, sG145R amino acid changes, which are known to alter immunogenicity.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation