HBV Mutation Detail Information

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Mutation Information

Mutation Site	G130D
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Relevant Drug	lamivudine (LAM)
Country	China

Literature Information

PubMed PMID	10320044
Disease	Liver cirrhosis
Published Year	1999
Journal	Antiviral research
Title	Hepatitis B virus variants with lamivudine-related mutations in the DNA polymerase and the 'a' epitope of the surface antigen are sensitive to ganciclovir.
Author	Oon CJ,Chen WN,Lim N,Koh S,Lim GK,Leong AL,Tan GS
Evidence	Here we report the identification of a novel type of lamivudine-related mutations located in both the polymerase (YM552DD-->Y1552DD) and the 'a' epitope of HBsAg (Gly130-->Asp130).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation