HIV Mutation Detail Information

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Mutation Information

Mutation Site	G12R
Mutation Type	Amino acid level
Gene/Protein/Region Type	Nef
Viral Reference	K03455.1
Country	Brazil

Literature Information

PubMed PMID	30201008
Clinical information	Yes
Disease	HIV infection/AIDS
Published Year	2018
Journal	Retrovirology
Title	Next-generation sequencing analyses of the emergence and maintenance of mutations in CTL epitopes in HIV controllers with differential viremia control.
Author	Caetano DG,Côrtes FH,Bello G,Teixeira SLM,Hoagland B,Grinsztejn B,Veloso VG,Guimarães ML,Morgado MG
Evidence	EC13 showed the highest number of Nef changes in mutation frequency, such as SNPs V10 K, G12R, M79I, and G140R, which became predominant at VL;in contrast, reversion to subtype B consensus Y and V residues were observed for Y135F and V148I.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation