HBV Mutation Detail Information

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Mutation Information
Mutation Site G129A
Mutation Type Amino acid level
Gene/Protein/Region Type S
Country Japan
Literature Information
PubMed PMID 11208474
Disease HBV infection
Published Year 2000
Journal Medical science monitor : international medical journal of experimental and clinical research
Title Analysis of HBs antigen negative variant of hepatitis B virus: unique substitutions, Glu129 to Asp and Gly145 to Ala in the surface antigen gene.
Author Koyanagi T,Nakamuta M,Sakai H,Sugimoto R,Enjoji M,Koto K,Iwamoto H,Kumazawa T,Mukaide M,Nawata H
Evidence However, the substitution of substitution glycine to alanine at position 129 introduce a putative glycosylation site (Asn-Gly-Thr), which may interfere with the antigenicity of HbsAg.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation